The Dana Andrews Collection is composed of 29 boxes. The collection focuses on the life, family, and acting career of Dana Andrews, as well as featuring the theater career and family of Mary Todd, Dana Andrews' wife.

Materials within the collection are mainly composed of photographs. Other materials include scrapbooks, correspondence, audiovisuals, magazines, programs, tickets, household documents, a ledger and diary, and materials about the Screen Actors Guild Inc.

The collection consists of one file containing correspondence, event invitations and flyers, and various other materials related to the San Francisco Public Library.