The Dana Andrews Collection is composed of 29 boxes. The collection focuses on the life, family, and acting career of Dana Andrews, as well as featuring the theater career and family of Mary Todd, Dana Andrews' wife.

Materials within the collection are mainly composed of photographs. Other materials include scrapbooks, correspondence, audiovisuals, magazines, programs, tickets, household documents, a ledger and diary, and materials about the Screen Actors Guild Inc.

This collection contains materials donated by Cathy Holm. Materials include newspapers and periodicals covering the assassination of President John F. Kennedy, as well as local newspapers from the 1990s.

The Newspaper Collection consists mainly of Texas newspapers as well as several titles from other states. Also represented are Centennial and Civil War Newspapers. The Newspaper collection includes both original and copied versions.